Maternal-foetal complications in pregnancy: a retrospective comparison between type 1 and type 2 diabetes mellitus

Abstract Background The aim of the study was a retrospective comparison differences in maternal-foetal outcomes between women with type 1 and 2 diabetes mellitus (T1DM T2DM). Methods A cohort 135 patients pregestational diabetes, 73 T1DM (mean age 29 ± 5 years) 62 T2DM 33 6 years), intensive insulin treatment throughout pregnancy were evaluated. Clinical metabolic parameters prevalence maternal foetal complications assessed. Results Women showed lower BMI ( p < 0.001), weight at delivery ?_total_insulin requirement (IR) first, second third trimesters (all 0.001) higher gain during HbA1c = 0.040), first 0.004), 0.020) 0.010) compared to T2DM. had risk macrosomia 0.005) than T2DM, while abortion 0.037) T1DM. At multivariate analysis, ?_total_IR trimester independently associated Conclusion have due pregnancy. By contrast, spontaneous T1DM, trimester.